| 名稱 | ALK p.F1174L Reference Standard |
| 型號 | CBP10225 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | ALK p.F1174L Reference Standard |
產(chǎn)品搜索
相關(guān)文章
- 【產(chǎn)品推介】腫瘤耐藥細(xì)胞株
- 科佰Bcr-AbL激酶細(xì)胞模型助力客戶發(fā)表高分文獻(xiàn)（IF 15.1）
- 從人結(jié)腸癌細(xì)胞株延伸出早期結(jié)腸癌治療方法
- 甲基丙二酸血癥（MMA）標(biāo)準(zhǔn)品上新
- 實(shí)驗(yàn)?zāi)芊裰貜?fù)仍在持續(xù)：誰來給韓春雨事件畫上句號？
- *針對肝癌的PD-1抗體獲FDA批準(zhǔn)，國產(chǎn)PD-1抗體進(jìn)入三期
- 細(xì)胞株購買為何比較看重生物等級？
- 神舟十一號成功發(fā)射！哪些生物實(shí)驗(yàn)跟著上天了？
- Z常用細(xì)胞系之top 5！
- 腸道守護(hù)者--GLP2R
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話：4008750250
號碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號
Email： zhangxiangwen@cobioer.com
電話：4008750250
號碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10225ALK p.F1174L Reference Standard
- 詳細(xì)內(nèi)容
CBP10225 | |
| Format | Genomic DNA |
| Description | ALK F1174L lies within the protein kinase domain of the Alk protein (UniProt.org). F1174L confers a gain of function to the Alk protein as indicated by transformation activity and increased cell proliferation in culture (PMID: 18923525, PMID: 29533785, PMID: 29907598), and has been demonstrated to occur as a secondary resistance mutation in the context of ALK fusions (PMID: 21030459). |
| Technical Data | |
| DNA Change | c.3522C>A |
| AA Change | p.F1174L |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 33.33% |
| Transcript | ENST00000389048 |
| Cosmic ID | COSM28055 |
| Chr position(GRCh37) | chr2:29443695 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
員_a.png)